Food Dye Effects: Hyperactivity, Cancer, & Allergies?

My childhood is full of memories triggered by curiosity. One of them has to do with making Easter eggs. I vividly remember squeezing drops of red food dye from that mini bottle into a bowl of water and then being amazed at how so few drops could transform the bowl to be so red.



Turns out that the power of food dye goes well beyond its color.



When I was growing up, food dye was just food dye. We primarily used it for cooking and crafts but it was also on the ingredient lists of plenty of foods but, no one cared. Nowadays the food dye effects have been linked to many different types of health concerns in kids, ranging from asthma to behavioral issues to allergies to ADHD to cancer.



But can these little drops of color really have that big of an impact on our children’s health?



Let’s dive in.

What Are Food Dyes Anyway?

Food dyes, also known as food coloring, are artificially created colorants that are used to give foods and beverages a particular color or to enhance their appearance.


Some of the most commonly used synthetic food dyes and foods that use them:

  1. Red 40

    • M&M’s, Gatorade, soda, Fruit Loops

  2. Yellow 5

    • Pickles, mustard, soup, apple sauce, salad dressing, shampoo

  3. Blue 1

    • Yogurt, Gatorade, popsicles, canned peas, mouthwash

  4. Green 3

    • Candy, ice cream, pudding, jellies, fish.

  5. Yellow 6

    • Chicken broth, Kraft Mac and Cheese, ice cream, hand soap, Pedialyte (interesting breakdown on that here).

  6. Red 3

    • Sausage casings, Marchiano cherries, candy, medicine.

  7. Blue 2

    • Cereal, ice cream, medicine, energy drinks.

  8. Citrus Red 2

    • Used for coloring the skin of non-organic Florida oranges.

  9. Red 2

    • Found only in the peels of some oranges.

Many products contain multiple food colorings to create specific colors. For example, many types of ice cream, cereal, and candy use 6 types of synthetic food colors (Yellow 6, Yellow 5, Blue 1, Blue 2, Red 3, and Red 40).



What’s In Food Dye?

Food dyes are typically derived from coal tar or petroleum. Yes, coal tar and petroleum.

Some food dyes may also contain trace amounts of heavy metals like lead, mercury, or arsenic.




Natural food dyes, on the other hand, are derived from sources like fruits, vegetables, and spices. For example, beet juice is often used as a natural red food dye, while turmeric is used as a natural yellow food dye. This does not mean that they are without their issues as we’ll learn later.




For the purposes of this article, we’ll be focusing primarily on synthetic food dyes.




Health Risks Of Food Dye

Food dyes are considered to be one of the most harmful food additives. The food industry uses 15 million pounds of food dye annually and, without regulation (more on that below), it’s increased by 500% in the last 50 years. Here are some of the major health concerns linked to food coloring.




ADHD

A study in Neurotherapeutics looked at the link between artificial food coloring and ADHD. They concluded that “AFCs are not a main cause of ADHD, but they may contribute significantly to some cases, and in some cases may additively push a youngster over the diagnostic threshold.”



Furthermore, the researchers had concerns about food dye effects in schools. “There may conceivably be a possible deleterious effect on classroom climate from most children deteriorating slightly, thus additively or even synergistically impairing the learning atmosphere.”



In a small study on 26 children with ADHD, 19 of them (73%) had a “significant improvement” in their symptoms when food dyes and preservatives were removed from their diet.



Another study looked at both 3-year-olds and 8 and 9-year-olds who did not have a diagnosis of ADHD. The children drank a mixture of artificial food dyes and/or sodium benzoate (a common food preservative) and noted “increased hyperactivity” in both age groups.



A review of food dyes, Toxicology of food dyes, found that "hypersensitivity reactions" have been the cause of Blue 1, Red 40, Yellow 5, and Yellow 6.



Finally, a meta-analysis of 15 double-blind placebo-controlled studies found that there is a higher prevalence of hyperactivity in children when they consume food coloring.




Cancer

Scientists conducted a study on rats by exposing them to Red 3 (erythrosine). They found an increased risk of thyroid tumors. The FDA partially banned Red 3 but then later reversed this ban. Red 40 has mostly replaced Red 3 although it’s still found in canned fruits, medicine, popsicles, candles, and Maraschino cherries, among other things.



The FDA, however, does recognize that artificial coloring such as Red 3 is a health concern. In fact, the FDA did ban Red 3 in cosmetics but they didn’t ban it for food. Why? Bureaucracy. Read more about this confusion in this Consumer Reports article.



The review of food dyes mentioned above found that benzidine and other cancer-causing agents have been found in Red 40, Yellow 5, and Yellow 6.

Do artificial dyes like Red 40 and Yellow 5 cause cancer? More research is needed to determine a link but it’s likely not helping and it’s probably not worth waiting for more research to come out to tell you if you should beating those Skittles.

Allergies

In a study on patients who already had allergies, yellow 5 created a variety of concerns including weakness, palpitations, blurred vision, and a runny nose.  There's also a correlation between an allergy to aspirin and food Yellow 5.  And for some reason, those allergic to aspirin are more likely to have an allergy to Yellow 5.



Even natural food colorings aren't immune from harm, as this study found.  "The present study indicates that natural food colours may induce hypersensitivity reactions as frequent as synthetic dyes."  They found reactions to food dyes occurred around 4 hours after ingestion.



In sum, a 2012 review of food dyes reports “that all of the nine currently US-approved dyes raise health concerns of varying degrees." This review called for dyes to be totally removed from foods due to limited testing as well as the evidence of health concerns.

Credit: Artificial Food Colors and Attention-Deficit/Hyperactivity Symptoms: Conclusions to Dye for

The FDA’s Stance

While more research is needed, it seems pretty clear that there’s a health concern. So, the FDA has done something about it, right?


Not exactly.


The FDA (Food and Drug Administration) has approved the use of synthetic food dyes in the United States and considers them safe for human consumption. While the FDA requires that food manufacturers list food dyes as ingredients, they maintain that food dyes are used in very small quantities and do not pose a significant health risk to the general population.


Yet, as mentioned above, they did ban Red 3 from being used in cosmetics because of health concerns.



In 2011, the FDA held a public hearing to discuss the potential health effects of synthetic food dyes, and while they ultimately concluded that more research was needed, they did not ban the use of food dyes in the United States.

Meanwhile, other countries, such as Norway, Finland, France, Austria, and the UK, have implemented restrictions or bans on certain food dyes due to these health concerns. McDonald’s in Britian thus colors their strawberry sundaes with real strawberries whereas McDonald’s in the U.S. use Red 40.

Tips For Avoiding Food Dyes

Ways to limit children's exposure to food dyes:


  • Choose whole foods: Choose real foods such as fruits and vegetables.

  • Read labels carefully: When buying packaged foods, read ingredient labels carefully and avoid products that contain synthetic food dyes. A good rule of thumb is to avoid products that have a number in their ingredient list (e.g. the “1’ in Blue 1). Look for products that are labeled with "no artificial colors."

  • Cook at home: Cooking meals at home allows you to control the ingredients and avoid added food dyes. Try making your own snacks and treats using natural ingredients.

  • Be aware of hidden sources. Pickles, farm-raised salmon, yogurt, popcorn, and protein bars are some of the many hidden sources of artificial dyes.

    • Tylenol is another one which is why we use Genexa instead.

    • Standard mouthwash also contains dyes so we use other brands like Hello. (More on mouthwash health concerns here.)



Takeaway

Food dyes are used to make foods look more attractive and they offer no nutritional benefit, for children and adults.


While more research needs to be conducted, the studies that do exist are “too substantial to dismiss”, as one study put it. The effects of food dye have been shown to increase the risk of hyperactivity, allergies, and even cancer.


While colors make things look more enticing, the risk isn’t worth the reward. The best way to avoid food dyes is to eat more whole foods and, when you do buy processed foods, look for “no artificial colors.”



Related:

Brian Comly

Brian Comly, M.S., OTR/L is the founder of MindBodyDad. He’s a husband, father, certified nutrition coach, and an occupational therapist (OT). He launched MindBodyDad.com and the podcast, The Growth Kit, as was to provide practical ways to live better.

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